1. Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma
Abundance of proteins matching selected subcellular locations (A–G) and functions (H–N). The numbers of proteins belonging to each class are given in the parentheses. The protein abundances were calculated on the basis of total spectral intensities of all quantified proteins. Red boxes indicate that the changes between cancer and normal were significant with P<0.01. Note that serum albumin levels (gray boxes) are similar between the three types of samples, indicating absence of differential contamination with plasma proteins. In (L), summed abundance of core and linker histones are shown by separate boxes. The purple boxes are for linker histones whereas the core histones by red boxes.
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Mol Syst Biol, Volume: 8, Issue: 1, First published: 11 September 2012, DOI: ( /msb )