1. Intercalated cells in rat collecting duct.
Intercalated cells in rat collecting duct. The cartoon and confocal micrograph illustrate the intercalated cell distribution along the kidney tubule and within the epithelium. Intercalated cells were detected in the cortical and outer medullary collecting duct (green oval) by immunoflorescence labeling using an antibody against one of the H+-ATPase subunits (green). Intercalated cells are also located in the connecting segment (red circle). The apical or luminal labeling of the H+-ATPase indicates that these cells are mostly type A intercalated cells (A-IC). Principal cells were labeled with an antibody against the water channel aquaporin-2 (red). Modified from reference 9, with permission.
Ankita Roy et al. CJASN 2015;10:
©2015 by American Society of Nephrology