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Advances in the heart-lung machine after John and Mary Gibbon

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Presentation on theme: "Advances in the heart-lung machine after John and Mary Gibbon"— Presentation transcript:

1 Advances in the heart-lung machine after John and Mary Gibbon
L.Henry Edmunds, MD  The Annals of Thoracic Surgery  Volume 76, Issue 6, Pages S2220-S2223 (December 2003) DOI: /j.athoracsur

2 Fig 1 Fibrin emboli in a cerebral vessel. In this study 31% of patients who died had nonfat cerebral emboli and 70% had fat emboli. (Reproduced with permission from Hill JD, et al. Ann Thorac Surg 1969;7:409–19.) The Annals of Thoracic Surgery  , S2220-S2223DOI: ( /j.athoracsur )

3 Fig 2 Measurements of F1.2, a protein fragment formed when prothrombin is cleaved to form thrombin, in 20 patients who had a variety of cardiac operations using cardiopulmonary bypass. Abbreviations indicate sample times and sites. *p less than 0.05 versus HEP sample by paired t statistic; †p less than PERC versus PERF. (HEP = after heparin, before CPB; PERF = perfusate sample taken 30 to 45 minutes after the start of CPB; PERC = sample taken simultaneously with PERF from the pericardial wound; POST = 5 minutes after stopping CPB; PROT = sample from the patient 15 minutes after protamine infusion.) (Reprinted with permission from Chung JH, et al. Circulation 1996;93:2014–8.) The Annals of Thoracic Surgery  , S2220-S2223DOI: ( /j.athoracsur )


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