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Published byReynold Doyle Modified over 5 years ago
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Fig. 6 Structural basis for the constitutive activity of US28.
Structural basis for the constitutive activity of US28. (A) Conformations of ArgICL2 in CCR5 (green; PDB ID: 4MBS; left), the US28 crystal structure (orange; center) and the US28 MD simulations (orange; right). (B) Schematic diagram of the network of side-chain interactions surrounding the DRY motif in CCR5 (left panel) and US28 (MD simulation; right). John S. Burg et al. Science 2015;347: Copyright © 2015, American Association for the Advancement of Science
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