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Published byTheophiel Hendrickx Modified over 5 years ago
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Lack of effect of topical finasteride suggests an endocrine role for dihydrotestosterone
Thomas M Price, M.D., Susan Allen, R.N., G.Vernon Pegram, M.D. Fertility and Sterility Volume 74, Issue 2, Pages (August 2000) DOI: /S (00)
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Figure 1 Serum levels of testosterone and dihydrotestosterone were compared by paired t-test at baseline, 3 months, and 6 months of topical finasteride therapy vs. placebo (mean ± SEM). A significant increase in testosterone was seen at 3 months in both the finasteride group (P=.038) and the placebo group (P=.044). There were no differences in testosterone between baseline and 6 months, or between groups. There were no differences in levels of dihydrotestosterone with time or between groups. Dihydrotestosterone: finasteride (□), placebo (■); testosterone: finasteride ( ), placebo ( ). Fertility and Sterility , DOI: ( /S (00) )
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