Presentation is loading. Please wait.

Presentation is loading. Please wait.

G3139 substitutes for heparin, which is required for the biological activity of FGF2. G3139 substitutes for heparin, which is required for the biological.

Published byRatna Sanjaya Modified over 5 years ago

Similar presentations

Presentation on theme: "G3139 substitutes for heparin, which is required for the biological activity of FGF2. G3139 substitutes for heparin, which is required for the biological."— Presentation transcript:

1 G3139 substitutes for heparin, which is required for the biological activity of FGF2.
G3139 substitutes for heparin, which is required for the biological activity of FGF2. C11 cells were washed twice with medium without interleukin-3 and seeded (2.2 × 104 per well in 48-well plates) in medium containing 10% fetal bovine serum but not interleukin-3. The cells were then treated with 1 nmol/L FGF2 + G3139 (1 μmol/L). After 2 d, proliferation was evaluated by sulforhodamine blue staining. Columns, average (n = 3); bars, SD. FGF2 + Hep versus FGF2: P < 0.001; FGF2 + G3139 versus FGF2: P < 0.002; G3139 or Hep versus control: P > 0.05 (not significant). Hep, heparin. C.A. Stein et al. Clin Cancer Res 2009;15: ©2009 by American Association for Cancer Research

Download ppt "G3139 substitutes for heparin, which is required for the biological activity of FGF2. G3139 substitutes for heparin, which is required for the biological."

Similar presentations

The expression and signaling of FGFR3 in WM cells.

The expression and signaling of FGFR3 in WM cells.
KG-501 suppresses NSCLC/IL-1β CM–induced migration of HUVECs by regulating IL-1β–induced CXC chemokine gene expression in NSCLC cells. KG-501 suppresses.

KG-501 suppresses NSCLC/IL-1β CM–induced migration of HUVECs by regulating IL-1β–induced CXC chemokine gene expression in NSCLC cells. KG-501 suppresses.
CDK2 is highly expressed in colon cancer cells and curcumin selectively suppresses HCT116 cell proliferation. CDK2 is highly expressed in colon cancer.

CDK2 is highly expressed in colon cancer cells and curcumin selectively suppresses HCT116 cell proliferation. CDK2 is highly expressed in colon cancer.
TDP1 knockdown increases the sensitivity of rhabdomyosarcoma cell lines to CPT treatment. TDP1 knockdown increases the sensitivity of rhabdomyosarcoma.

TDP1 knockdown increases the sensitivity of rhabdomyosarcoma cell lines to CPT treatment. TDP1 knockdown increases the sensitivity of rhabdomyosarcoma.
SIRT1 is downregulated in human gastric cancer (GC).

SIRT1 is downregulated in human gastric cancer (GC).
SW fraction induces S phase arrest and apoptosis.

SW fraction induces S phase arrest and apoptosis.
Thiocolchicoside suppresses cell proliferation and colony formation of various cancer cell lines. Thiocolchicoside suppresses cell proliferation and colony.

Thiocolchicoside suppresses cell proliferation and colony formation of various cancer cell lines. Thiocolchicoside suppresses cell proliferation and colony.
Recognition of naturally processed HTLV-1 Tax protein derived from HAM patient's PBMC. A, HTLV-1 Tax protein content was evaluated by Western blot analysis.

Recognition of naturally processed HTLV-1 Tax protein derived from HAM patient's PBMC. A, HTLV-1 Tax protein content was evaluated by Western blot analysis.
Immunohistochemical detection of 8-OHdG by use of the 1F7 monoclonal antibody in oligomer-treated PC3 prostate cancer cells. a, control untreated peripheral.

Immunohistochemical detection of 8-OHdG by use of the 1F7 monoclonal antibody in oligomer-treated PC3 prostate cancer cells. a, control untreated peripheral.
CDCP1 is required for invadopodia formation and ECM degradation by human breast cancer cells. CDCP1 is required for invadopodia formation and ECM degradation.

CDCP1 is required for invadopodia formation and ECM degradation by human breast cancer cells. CDCP1 is required for invadopodia formation and ECM degradation.
Tumor MMP-1 functionally regulates the permeability of endothelial cell barriers and contributes to HEp3-hi/diss transendothelial migration. Tumor MMP-1.

Tumor MMP-1 functionally regulates the permeability of endothelial cell barriers and contributes to HEp3-hi/diss transendothelial migration. Tumor MMP-1.
A, Overall survival of patients treated with CAR T cells (black line; n = 15). A, Overall survival of patients treated with CAR T cells (black line; n.

A, Overall survival of patients treated with CAR T cells (black line; n = 15). A, Overall survival of patients treated with CAR T cells (black line; n.
Colony-forming capacity of CD34+ cells with and without CLL-1 expression. Colony-forming capacity of CD34+ cells with and without CLL-1 expression. CD34+

Colony-forming capacity of CD34+ cells with and without CLL-1 expression. Colony-forming capacity of CD34+ cells with and without CLL-1 expression. CD34+
Selectivity of SHAL binding to human B-cell lymphoma cell lines.

Selectivity of SHAL binding to human B-cell lymphoma cell lines.
Β-Cryptoxanthin at a concentration of 10 μmol/L decreases proliferation in HCT116 cells after 6 and 8 days of treatment. β-Cryptoxanthin at a concentration.

Β-Cryptoxanthin at a concentration of 10 μmol/L decreases proliferation in HCT116 cells after 6 and 8 days of treatment. β-Cryptoxanthin at a concentration.
Radiosensitization by combined Wee1 and PARP inhibition.

Radiosensitization by combined Wee1 and PARP inhibition.
Mitotic catastrophe symptoms caused by curcumin are followed by apoptosis. Mitotic catastrophe symptoms caused by curcumin are followed by apoptosis. A.

Mitotic catastrophe symptoms caused by curcumin are followed by apoptosis. Mitotic catastrophe symptoms caused by curcumin are followed by apoptosis. A.
FOXO1 inhibits Runx2-induced invasion of prostate cancer cells.

FOXO1 inhibits Runx2-induced invasion of prostate cancer cells.
Binding and internalization of bispecific immunotoxins.

Binding and internalization of bispecific immunotoxins.
The effects of IAA and glycyrrhizin (Gc) on proliferation and cell-cycle distribution. The effects of IAA and glycyrrhizin (Gc) on proliferation and cell-cycle.

The effects of IAA and glycyrrhizin (Gc) on proliferation and cell-cycle distribution. The effects of IAA and glycyrrhizin (Gc) on proliferation and cell-cycle.

Similar presentations

Ads by Google