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Integrative Physiology II: Fluid and Electrolyte Balance

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1 Integrative Physiology II: Fluid and Electrolyte Balance
Chapter 20 Integrative Physiology II: Fluid and Electrolyte Balance

2 Response to decreased or elevated Blood Pressure
Figure 20-1: Integrated responses to changes in blood volume and blood pressure

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4 Figure 20-2: Water balance in the body
Body Water Balance Drinking & eating provides water Kidney conserves water so output = intake Figure 20-2: Water balance in the body

5 Figure 20-3: Role of the kidneys in water balance
Body Water Balance Figure 20-3: Role of the kidneys in water balance

6 Water Balance Reflex: Regulators of Vasopressin Release
Figure 20-7: Factors affecting vasopressin release

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9 Sodium Balance: Intake & Excretion
Figure 20-11: Homeostatic responses to eating salt

10 Angiotensin Pathway: Maintains BP , Volume & Osmolarity Angiotensinogen, ANGI, ANG II, rennin, & ACE
Figure 20-13: The renin-angiotensin-aldosterone pathway

11 Artial Naturetic Peptide: Regulates Na+ & H2O Excretion
Figure 20-15: Atrial natriuretic peptide

12 Response to Dehydration & Osmolarity Imbalance
Figure : Homeostatic compensation for severe dehydration

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14 Acid/Base Homeostasis: Overview
Acidosis:  plasma pH Protein damage CNS depression Alkalosis:  plasma pH Hyperexcitability CNS & heart Buffers: HCO3- & proteins H+ input: diet & metabolic H+ output: lungs & kidney

15 Acid/Base Homeostasis: Overview
Figure 20-18: Hydrogen balance in the body

16 Kidney Hydrogen Ion Balancing: Collecting Duct
Type A Intercalated cells excrete H+ absorb HCO3- Type B intercalated cells absorb H+ secrete HCO3-

17 Kidney Hydrogen Ion Balancing: Collecting Duct
Figure 20-22: Role of the intercalated cell in acidosis and alkalosis

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23 Classifications of Acute Kidney Injury and Chronic Kidney Disease.

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