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Disease severity and classification agreement between methods: schematic representation of the principle that classification agreement between two methods of measurement (or diagnostic accuracy if one is seen as a reference gold standard) varies across the ... Disease severity and classification agreement between methods: schematic representation of the principle that classification agreement between two methods of measurement (or diagnostic accuracy if one is seen as a reference gold standard) varies across the range of disease severity. At the extremes of disease and health agreement is 100%. Close to the classification cut-off, around the intermediate range of disease severity, agreement falls, reaching a nadir close to 50%. Ricardo Petraco et al. Open Heart 2018;5:e000663 ©2018 by British Cardiovascular Society
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