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Improving Management of Acute HTN in Patients With Stroke

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Presentation on theme: "Improving Management of Acute HTN in Patients With Stroke"— Presentation transcript:

1 Improving Management of Acute HTN in Patients With Stroke

2

3 Case: ED Presentation

4 2018 AHA/ASA Guidelines For Early Management of Patients With Acute Ischemic Stroke

5 AIS Management Initial Assessment

6 Case Further Details

7 Prevalence of Elevated BP Across Stroke Subtypes

8 Factors Contributing to HTN in Stroke

9 Benefits of Controlling HTN in Stroke

10 BP Control

11 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ ASPC/NMA/PCNA Guidelines

12 VELOCITY Clevidipine for Treatment of Acute Severe HTN

13 BP Excursions and Stroke Outcome

14 Treatment Options For Arterial HTN in Patients With AIS Eligible For Acute Reperfusion Therapy

15 Variable BP Response of IV Labetalol and Nicardipine

16 Pharmacokinetic Profile of IV Antihypertensive Agents for AIS

17 ENCHANTED Intensive vs Guideline-Recommended BP Lowering in Patients Treated With Thrombolysis For AIS

18 ENCHANTED Primary and Safety Outcomes

19 Antihypertensive Agents Different Pharmacology, Different Effects

20 Hemodynamic Phenotypes of Suspected Stroke Patients in the ED

21 Case Continued: Antihypertensive Treatment

22 Efficacy of Antihypertensive Agents in AIS

23 AIS Management Hemodynamic Management During Revascularization And Post-Intervention Phases

24 CATIS Effect of Immediate BP Reduction in Patients With AIS Not Treated With Thrombolytic or Endovascular Therapy

25 HTN in Patients with AIS Not Treated With Thrombolytic or Endovascular Therapy

26 No Overall Substantial Change In Cerebral Blood Flow With Rapid Reduction of Severely Elevated BP in ED

27 Cerebral Autoregulation in Health, Chronic HTN, And Acute Ischemia

28 Therapeutic Changes In BP And Outcomes in Acute Stroke Metaregression Analysis

29 Summary General Stroke Care

30 Summary Patients With AIS And HTN

31 Abbreviations

32 Abbreviations (cont)


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