1. Zinc Deficiency Presenting with Necrolytic Acral Erythema and Coma
Baruch D. Jakubovic, MD, Jonathan S. Zipursky, MD, Natalie Wong, MD, Michele McCall, RD, MSc, Henry R. Jakubovic, MD, Vincent Chien, MD 
The American Journal of Medicine 
Volume 128, Issue 8, Pages e3-e4 (August 2015)
DOI: /j.amjmed
Copyright © 2015 Elsevier Inc. Terms and Conditions

2. Figure
A, Necrolytic acral erythema, gross findings. Images captured on presentation depicting symmetric involvement of the dorsal surfaces of the feet. Lesions were initially erythematous and macular, but soon became plaque-like and confluent, with underlying edema and focal areas of vesiculation. Note the striking demarcation from the normal-appearing surrounding skin. B, Necrolytic acral erythema, histopathology. Light microscopy of a hematoxylin-eosin-stained punch biopsy obtained from the dorsal foot. The most notable finding is the significant epidermal necrosis involving the outer one third of the epidermis. There was also an associated sparse superficial perivascular lymphoid infiltrate.
The American Journal of Medicine  , e3-e4DOI: ( /j.amjmed )
Copyright © 2015 Elsevier Inc. Terms and Conditions