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The 800-nm diode laser in the treatment of leg veins: Assessment at 6 months  Mario A. Trelles, MD, PhD, Ines Allones, MD, Javier Álvarez, MD, Mariano.

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Presentation on theme: "The 800-nm diode laser in the treatment of leg veins: Assessment at 6 months  Mario A. Trelles, MD, PhD, Ines Allones, MD, Javier Álvarez, MD, Mariano."— Presentation transcript:

1 The 800-nm diode laser in the treatment of leg veins: Assessment at 6 months 
Mario A. Trelles, MD, PhD, Ines Allones, MD, Javier Álvarez, MD, Mariano Vélez, MD, Manuel Martín-Vázquez, PhD, Oswaldo R. Trelles, PhD, Ricardo Luna, MD, Carmen Buil, MD, Serge R. Mordon, PhD  Journal of the American Academy of Dermatology  Volume 54, Issue 2, Pages (February 2006) DOI: /j.jaad Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Changes over time course in vessel diameter, vessel appearance, and erythema. Plotting shows mean scores for all patients. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Example of computer assessment of clearance index. Assessment before (A) and after (B) 6 months of treatment in typical venous lesion. Edge detector—based markings for same images are seen in C and D. Inset table shows pixel-based areas and number of discrete spots for same time points, allowing percentage calculation of improvement. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions

4 Fig 3 Typical example of histologic assessment. A, In pretreatment findings, dilated varicose vein is clearly visible. B, In immediate posttreatment findings, vessel has closed with fibrosclerotic changes in vessel lumen, surrounded by coagulated collagen fibers. C, Higher magnification permits detailed observation of changes to vessel wall morphology, with apparent damage to intima coupled with sclerotic reaction. D, Immunostaining with anti-CD34 antibody at higher magnification shows positive staining, demonstrating destructive fibrotic changes to vessel wall and hyalinization phenomenon in collagen fibers. (A, B, and C, Masson trichromic stain; original magnifications: A and B, ×125; C and D, ×250.) Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions

5 Fig 4 Leg veins in upper aspect of left thigh of 55-year-old woman (patient 1) before (A) and 6 months after (B) final treatment with very good results. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions

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