1. Population pharmacokinetics of tobramycin administered thrice daily and once daily in children and adults with cystic fibrosis 
D.J. Touw, A.J. Knox, A. Smyth 
Journal of Cystic Fibrosis 
Volume 6, Issue 5, Pages (September 2007)
DOI: /j.jcf
Copyright © 2007 European Cystic Fibrosis Society. Terms and Conditions

2. Fig. 1
Relationship between volume of distribution per kg body weight and age. Diamonds: paediatric patients receiving tobramycin once daily, squares: paediatric patients receiving tobramycin three times daily, triangles: adult patients receiving tobramycin once daily and crosses: adult patients receiving tobramycin three times daily.
Journal of Cystic Fibrosis 2007 6, DOI: ( /j.jcf )
Copyright © 2007 European Cystic Fibrosis Society. Terms and Conditions

3. Fig. 2
Relationship between renal elimination rate per ml/min/1.73 m2 creatinine clearance and age. Diamonds: paediatric patients receiving tobramycin once daily, squares: paediatric patients receiving tobramycin three times daily, triangles: adult patients receiving tobramycin once daily and crosses: adult patients receiving tobramycin three times daily.
Journal of Cystic Fibrosis 2007 6, DOI: ( /j.jcf )
Copyright © 2007 European Cystic Fibrosis Society. Terms and Conditions