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Fig. 1 IDH3α expression is elevated in human-derived gliomas.

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Presentation on theme: "Fig. 1 IDH3α expression is elevated in human-derived gliomas."— Presentation transcript:

1 Fig. 1 IDH3α expression is elevated in human-derived gliomas.
IDH3α expression is elevated in human-derived gliomas. (A) IDH3α, IDH3β, and IDH3γ mRNA expression as determined by RNA-seq of 122 RNA samples from 10 regionally dissected GBM tumors (obtained from the Ivy GAP, (B) Representative images of IDH3α IHC stainings with different grading scores. Scale bar, 50 μm. H&E, hematoxylin and eosin. (C) TMAs of GBM patient tumor samples, obtained from the University of Kentucky, and GBM tissue blocks containing tumor tissue of the leading edge were stained with IDH3α antibody, and expression was quantified in glial cells of nontumor brain versus GBM tumor cells. *P = 0.03, one-way analysis of variance (ANOVA); n = 8 for nontumor, n = 87 for cellular tumor samples, n = 12 for leading edge. Jasmine L. May et al. Sci Adv 2019;5:eaat0456 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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