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Human Tfr cells do not express CD25.

Published byΠερσεφόνη Παπακωνσταντίνου Modified over 5 years ago

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Presentation on theme: "Human Tfr cells do not express CD25."— Presentation transcript:

1 Human Tfr cells do not express CD25.
Human Tfr cells do not express CD25. (A) Flow cytometry contour plots showing CD4+Foxp3− and CD4+Foxp3+ T cells (left); CXCR5hiPD-1hi Tfh cells (blue) and CXCR5int/loPD-1int/lo Teff cells (cyan) within CD4+Foxp3− T cells (middle); and CXCR5hiPD-1hi Tfr cells (red) and CXCR5int/loPD-1int/lo Treg cells (green) within CD4+Foxp3+ T cells (right). (B) Histograms showing CD25 expression level (left) and MFI (right) on gated subsets from (A). (C) Flow cytometry contour plot identifying different subsets according to PD-1 and CXCR5 expression within CD4+Foxp3+ T cells (left) and the corresponding expression of CD25 (right). (D) Histograms showing the IL-1R2 expression level of the subsets mentioned above (left) and their MFI (right). (B and D) n = 5; *P < 0.05, **P < 0.01, Mann-Whitney U test. Paul-Gydeon G. Ritvo et al. Sci. Immunol. 2017;2:eaan0368 Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works

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