1. The Asthma Treatment Gap

2. Introduction

3. Goals of Asthma Management

4. Fighting for Breath Survey

5. Still Fighting for Breath Survey

6. Impact of Asthma on Psychological Wellbeing

7. Most Prevalent Expanded Diagnosis Cluster > 10%

8. Impact of Asthma on Daily Activities With Severe Persistent Asthma

9. Reasons for Poor Asthma Control

10. Uncontrolled and Difficult-to-treat Asthma

11. Recommendations in Step 4 and 5 Patients

12. Assess and Treat Severe Asthma Phenotypes

13. Management of Severe Asthma

14. Step 5: Refer for Phenotypic Investigation and Add-on Therapy

15. Fevipiprant in Patients With Persistent Eosinophilic Asthma

16. Effect of Azithromycin on Asthma Exacerbations in Persistent Uncontrolled Asthma 

17. Bronchial Thermoplasty

18. DP2 and Airway Smooth Muscle Cells

19. Conclusion

20. Abbreviations