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12-Hydroxyeicosatetraenoic acid levels are increased in actinic keratoses and squamous cell carcinoma  Vivian Laquer, MD, Ryan W. Dellinger, PhD, Irene.

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Presentation on theme: "12-Hydroxyeicosatetraenoic acid levels are increased in actinic keratoses and squamous cell carcinoma  Vivian Laquer, MD, Ryan W. Dellinger, PhD, Irene."— Presentation transcript:

1 12-Hydroxyeicosatetraenoic acid levels are increased in actinic keratoses and squamous cell carcinoma  Vivian Laquer, MD, Ryan W. Dellinger, PhD, Irene Mannering, MD, Angela Gomez Garcia, BS, Vivek Abraham, BS, Janelle Pavlis, MD, Feng Liu-Smith, PhD, Sebastien De Feraudy, MD, Frank L. Meyskens, MD, Kristen M. Kelly, MD  Journal of the American Academy of Dermatology  Volume 79, Issue 6, Pages (December 2018) DOI: /j.jaad Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 12-HETE levels in nonlesional skin, AKs, and SCC. 12-HETE levels were measured in nonlesional skin, AKs, and SCCs, and 12-HETE was found to be elevated in AK and SCC skin. 12-HETE, 12-Hydroxyeicosatetraenoic acid; AK, actinic keratosis; SCC, squamous cell carcinoma. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Immunohistochemical staining of UDP-glucuronosyltransferases UGT1A and UGT2B in nonlesional skin and SCC skin. SCC, Squamous cell carcinoma. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions


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