1. Mean changes (standard error) from baseline in A1C (A and B) and body weight (C and D) for patients with type 1 (A and C) or type 2 (B and D) diabetes treated with placebo + insulin or pramlintide + insulin.
Mean changes (standard error) from baseline in A1C (A and B) and body weight (C and D) for patients with type 1 (A and C) or type 2 (B and D) diabetes treated with placebo + insulin or pramlintide + insulin. From ref. 52 and ref. 53. Statistical significance is denoted by * (P < 0.05) and ** (P < 0.001). In both types of diabetes, addition of pramlintide to existing insulin therapy led to significant and sustained reductions in both A1C and body weight.
John B. Buse et al. Clin Diabetes 2002;20:
©2002 by American Diabetes Association