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A phase II dose-ranging study of the phosphodiesterase inhibitor K-134 in patients with peripheral artery disease and claudication  Eric P. Brass, MD,

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Presentation on theme: "A phase II dose-ranging study of the phosphodiesterase inhibitor K-134 in patients with peripheral artery disease and claudication  Eric P. Brass, MD,"— Presentation transcript:

1 A phase II dose-ranging study of the phosphodiesterase inhibitor K-134 in patients with peripheral artery disease and claudication  Eric P. Brass, MD, PhD, Leslie T. Cooper, MD, Roger E. Morgan, MD, William R. Hiatt, MD  Journal of Vascular Surgery  Volume 55, Issue 2, Pages e1 (February 2012) DOI: /j.jvs Copyright © 2012 Society for Vascular Surgery Terms and Conditions

2 Fig Flow chart shows patient disposition. The modified intention-to-treat (mITT) population included randomized patients who completed the study plus patients who withdrew from the study after a postrandomization treadmill test. AE, Adverse event. *Number of withdrawn patients with postrandomization treadmill results. There were no statistical differences in the withdrawal rates between the placebo, 500-mg K-134, 100-mg K-134, and cilostazol arms using χ2 (P = .429). Journal of Vascular Surgery  , e1DOI: ( /j.jvs ) Copyright © 2012 Society for Vascular Surgery Terms and Conditions

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