1. What's New in Rare CKDs?

3. Challenge With Rare CKDs

4. Exome Sequencing in Kidney Disease

5. Clinical Implications of Exome Sequencing

6. Pathway for Renal Disease Progression

7. New Treatment Target in CKD

8. Bardoxolone Mechanism of Action

9. Chronic Inflammation Plays a Central Role in CKD Progression

10. Bardoxolone in ADPKD

11. Treatment of ADPKD: Combining Complementary Mechanisms

12. Problems Faced When Dealing With PKD

13. Multiple Drug Approach to Treatment of CKD

14. Exclusion of At-Risk Patients in BEACON Appears to Improve Risk-Benefit Profile of Bardoxolone

15. PHOENIX Study Bardoxolone in Patients With Rare CKDs

16. PHOENIX: FSGS Population

17. Increases in Urinary Protein Are Consistent With Increases in GFR and Not Injury

18. CARDINAL Study Phase 2 Study in Patients With Alport Syndrome

19. Abbreviations

20. Abbreviations (cont)

21. Abbreviations (cont)