1. A, effect of IP6 feeding on the weight of LUT organs normalized to body weight.
A, effect of IP6 feeding on the weight of LUT organs normalized to body weight. B, IP6 feeding reduces prostate volume in TRAMP mice as assessed by MRI, conducted as a function of time. Error bars indicate ± SEM. C, longitudinal assessment of prostate/tumor volume in TRAMP mice using noninvasive proton density-weighted MRI during IP6 feeding over a time period of 24 weeks, starting from 4 weeks till 28 weeks of mice age. Representative coronal PD MRI images (6 TRAMP mice per each group were subjected to MRI) of prostate size are presented for untreated control (top), 2% IP6-fed (middle), and 4% IP6-fed mice (bottom). The prostate location and size are depicted as yellow [regions of interest (ROI) on each image]. NS, not significant.
Komal Raina et al. Cancer Prev Res 2013;6:40-50
©2013 by American Association for Cancer Research