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Carbon monoxide (CO) delivery system used in animal models and Phase 1 clinical trials. Carbon monoxide (CO) delivery system used in animal models and.

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Presentation on theme: "Carbon monoxide (CO) delivery system used in animal models and Phase 1 clinical trials. Carbon monoxide (CO) delivery system used in animal models and."— Presentation transcript:

1 Carbon monoxide (CO) delivery system used in animal models and Phase 1 clinical trials.
Carbon monoxide (CO) delivery system used in animal models and Phase 1 clinical trials. A: Front view. B: Schematic including ventilator, CO delivery system with injector module, and CO gas cylinder. C: Volumetric mixing data using the CO delivery system, a mechanical ventilator, and test lung. Flow-matching results in instantaneous flow of CO gas proportional to the inspiratory flow (Vent Flow) to deliver and maintain a precise and constant CO concentration. From Reference 95, with permission. Dean R Hess Respir Care 2017;62: (c) 2012 by Daedalus Enterprises, Inc.

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The patient is being ventilated with 2 types of breaths.

The patient is being ventilated with 2 types of breaths.
The changes in peak flow and inspiratory time between a minimum rise time (first 2 breaths) and a maximum rise time (last 2 breaths), with the Servo-i.

The changes in peak flow and inspiratory time between a minimum rise time (first 2 breaths) and a maximum rise time (last 2 breaths), with the Servo-i.
Airway pressure and flow waveforms during constant flow volume control ventilation, illustrating the effect of an end-inspiratory breath-hold. Airway pressure.

Airway pressure and flow waveforms during constant flow volume control ventilation, illustrating the effect of an end-inspiratory breath-hold. Airway pressure.
Air flow during ventilator-supported speech production.

Air flow during ventilator-supported speech production.
Lung CT images were obtained while tracing the curve in static conditions. Lung CT images were obtained while tracing the curve in static conditions. Note.

Lung CT images were obtained while tracing the curve in static conditions. Lung CT images were obtained while tracing the curve in static conditions. Note.
Schematic illustration of upper airway anatomical dead space volume (VD) during unidirectional breathing. Schematic illustration of upper airway anatomical.

Schematic illustration of upper airway anatomical dead space volume (VD) during unidirectional breathing. Schematic illustration of upper airway anatomical.
Lung simulator diagram of airway pressure release ventilation (APRV): volume (yellow), lung pressure (white), and flow (orange)/time curve. Lung simulator.

Lung simulator diagram of airway pressure release ventilation (APRV): volume (yellow), lung pressure (white), and flow (orange)/time curve. Lung simulator.
Trigger delays and leaks.

Trigger delays and leaks.
The 3-compartment lung model described by Riley and Cournand151,152 represents gas exchange in the lung in regard to the matching of alveolar gas volume.

The 3-compartment lung model described by Riley and Cournand151,152 represents gas exchange in the lung in regard to the matching of alveolar gas volume.
HomeLOX liquid oxygen system, which creates oxygen from a concentrator and refrigerates the concentrator gas to a liquid state, which is stored in a small.

HomeLOX liquid oxygen system, which creates oxygen from a concentrator and refrigerates the concentrator gas to a liquid state, which is stored in a small.
The Spectrum mask incorporates the leak port into the circuit, whereas the Mirage mask incorporates the leak port into the mask. The Spectrum mask incorporates.

The Spectrum mask incorporates the leak port into the circuit, whereas the Mirage mask incorporates the leak port into the mask. The Spectrum mask incorporates.
Shape-signal method of triggering combines shape signal (A) and volume (B) methods of triggering. Shape-signal method of triggering combines shape signal.

Shape-signal method of triggering combines shape signal (A) and volume (B) methods of triggering. Shape-signal method of triggering combines shape signal.
A ventilator and TTL test lung were used to simulate spontaneous breathing. A ventilator and TTL test lung were used to simulate spontaneous breathing.

A ventilator and TTL test lung were used to simulate spontaneous breathing. A ventilator and TTL test lung were used to simulate spontaneous breathing.
Several potential sources of error in esophageal manometry are illustrated in this transverse section of the thorax. Several potential sources of error.

Several potential sources of error in esophageal manometry are illustrated in this transverse section of the thorax. Several potential sources of error.
The high flow nasal cannula (HFNC) system incorporated an air/O2 blender with a flow meter and a heated humidifier. The high flow nasal cannula (HFNC)

The high flow nasal cannula (HFNC) system incorporated an air/O2 blender with a flow meter and a heated humidifier. The high flow nasal cannula (HFNC)
Noninvasive ventilation-neurally adjusted ventilatory assist (NIV-NAVA) where each patient effort is captured but support is insufficient (maximum electrical.

Noninvasive ventilation-neurally adjusted ventilatory assist (NIV-NAVA) where each patient effort is captured but support is insufficient (maximum electrical.
An example of delayed cycling during pressure-support ventilation of a patient with COPD, on a Puritan Bennett 7200 ventilator, which has a flow-termination.

An example of delayed cycling during pressure-support ventilation of a patient with COPD, on a Puritan Bennett 7200 ventilator, which has a flow-termination.
Simulated screenshot of flow starvation in volume control continuous mandatory ventilation. Simulated screenshot of flow starvation in volume control continuous.

Simulated screenshot of flow starvation in volume control continuous mandatory ventilation. Simulated screenshot of flow starvation in volume control continuous.
Characteristics of a pressure-supported breath.

Characteristics of a pressure-supported breath.
A: Schematic representation of the heterogeneity of the lungs of patients with ARDS. Normal alveoli are subject to injury due to overdistention, whereas.

A: Schematic representation of the heterogeneity of the lungs of patients with ARDS. Normal alveoli are subject to injury due to overdistention, whereas.

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