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Acanthosis nigricans in a patient with sarcoma of unknown origin

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Presentation on theme: "Acanthosis nigricans in a patient with sarcoma of unknown origin"— Presentation transcript:

1 Acanthosis nigricans in a patient with sarcoma of unknown origin
Kay Dietmar Brantsch, MD, Matthias Moehrle, MD  Journal of the American Academy of Dermatology  Volume 62, Issue 3, Pages (March 2010) DOI: /j.jaad Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Right axilla showing acanthosis nigricans and a subcutaneous mass. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Tumor specimen after extirpation from the right axilla.
Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions

4 Fig 3 Skin biopsy showing acanthosis, papillomatosis, hyperkeratosis, and increased dermal pigmentation. (Hematoxylin–eosin stain; original magnification: ×20.) Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions

5 Fig 4 Histology of the axillary tumor showing proliferating cells, hyperchromatic, polymorphic nuclei, an altered cytoplasm to nucleus ratio, and many prominent eosinophilic nucleoli. (Hematoxylin–eosin stain; original magnification: ×200.) Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions

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