1. Fig. 1. Levels of Th2 and Th17 cytokines in HDM-induced mouse model of asthma. (A) The design of the HDM-induced mouse model of asthma. (B) The numbers of lymphocytes, eosinophils, neutrophils and macrophages in the BALF were evaluated 48 hours after the last HDM challenge. (C) The ARH to Mch were measured 24 hours after the last HDM challenge. (D) The levels of HDM-specific IgE and IgG1 in BALF were measured by ELISA. (E) IL-4, IL-5, and IL-13 levels in BALF were quantified by ELISA. (F) IL-17A and TGF-β1 levels in BALF were measured by ELISA. The results are representative of 3 independent experiments (n = 3–5). Data represent mean ± standard error of the mean.
Th, T helper; HDM, house dust mite; BALF, bronchoalveolar lavage fluid; AHR, airway hyperreactivity; Mch, methacholine; Ig, immunoglobulin; ELISA, enzyme-linked immunosorbent assay; IL, interleukin; ns, not significant.
*P < 0.05, †P < 0.01, ‡P <
Fig. 1. Levels of Th2 and Th17 cytokines in HDM-induced mouse model of asthma. (A) The design of the HDM-induced mouse model of asthma. (B) The numbers of lymphocytes, eosinophils, neutrophils and macrophages in the BALF were evaluated 48 hours after the last HDM challenge. (C) The ARH to Mch were measured 24 hours after the last…
Allergy Asthma Immunol Res Sep;10(5):