1. Noise exposure increased p-LKB1 in the cochlea
Noise exposure increased p-LKB1 in the cochlea. a, Cochlear sections showed increased DAB-stained immunolabeling of p-LKB1 (brown) in the cytosol and nuclei of OHCs, IHCs, and supporting cells of the organ of Corti (OC), SGNs, basal cells of the stria vascu...
Noise exposure increased p-LKB1 in the cochlea. a, Cochlear sections showed increased DAB-stained immunolabeling of p-LKB1 (brown) in the cytosol and nuclei of OHCs, IHCs, and supporting cells of the organ of Corti (OC), SGNs, basal cells of the stria vascularis, and fibrocytes of the spiral ligament (Stria) 1 h after 98 dB exposure compared with unexposed controls. Representative images were taken from the basal turn. Scale bar, 10 μm. b, b′, Western blots using total cochlear homogenates showed increased p-LKB1 1 h after 98 dB exposure compared with unexposed controls. GAPDH served as the sample loading control; n = 5. Data are presented as the mean ± SD. *p < 0.05.
Kayla Hill et al. J. Neurosci. 2016;36:
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