2. Kaplan Meier and diagnostics

3. Regression effect process

4. Effective sample size

5. Basic probabilities

6. expectations and variances

7. regression effect process

8. regression effect process

9. behavior of regression effect process

10. large sample theory

11. large sample theory

12. regression effect process under H1

13. Large sample result

14. Brownian bridge

15. example in breast cancer study

16. confidence bands

17. confidence bands under PH

18. change point model

19. changepoint estimation

20. Freireich data

21. NPH Curie data

22. mild NPH Curie data

23. Curie breast cancer data

24. Curie receptor status

25. Receptor – cutpoint model

26. weighted log-rank tests

27. Log-rank and DOT

28. area under curve test

29. integrated log-rank

30. area under curve and log-rank

31. covariance of AUC and DOT

32. AOC - immunotherapy

33. NPH concave

34. % non-responders - convex effects

35. MRC clinical trial lung
p-value = 0.09 log-rank p-value = AUC test