1. Alan B. MacDonald, M.D., FCAP
Alzheimer’s Disease:
Signs in the Peripheral Blood:
Amyloid deposits
On Circulating living Borrelia Biofilms
Alan B. MacDonald, M.D., FCAP
October 9, 2015
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

2. Actual Particles of amyloid Huge in size in Blood smears
30microns to over 100 microns
In diameter
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

3. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved
Congo Red Stain
For
Amyloid
Positive
----
Blood smear
Dementia patient
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

4. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved
Miyamotoi
Borrelia
DNA Probe
BLOOD :
Circulating
Borrelia
Mixed species
Biofilm
Communities
FISH method
Burgdorferi
Borrelia
DNA Probe
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

5. Single species Biofilm Community
Blood
DNA probe
For
Burgdorferi Borrelia
FISH Method
Single species Biofilm Community
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

6. Single Species Biofilm Community
Blood
DNA Probe
For
Miyamotoi Borrelia
FISH method
Single Species Biofilm Community
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

7. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved
Congo Red Stain
Peripheral blood
Dementia patient --
Huge Particle
Of Amyloid/biofilm
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

8. Amyloid /biofilm Particle in blood
One Red Blood Cell – Diameter 7 microns
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

9. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved
BLOOD
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

10. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved
BLOOD
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

11. In Blood Amyloid /Biofilm Particle Very Large-
Notice the Birefringence
Some Red areas and
Some Green areas
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

12. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved
Green arrows
Point to
Green Birefringence
In the
Amyloid / biofilm
BLOOD Smear
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

13. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved
BLOOD Smear
Black Arrows
Point to
The Water Channel
Empty spaces
In the Biofilm
Community
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

14. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved
Amyloid Coated
Biofilm
Communities
In Blood -
Dementia patient
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

15. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved
Congo Red stain
Red birefringence
BLOOD
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

16. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

17. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

18. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved
Alzheimer’s
Disease
Autopsy
Brain
With
Amyloid/biofilm
Plaques
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

19. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved
Alzheimer’s
Disease
Autopsy
Brain
With
Amyloid/biofilm
Plaques
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

20. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved
Alzheimer’s
Disease
Autopsy
Brain
With
Amyloid/biofilm
Plaques
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

21. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved
Alzheimer’s
Disease
Autopsy
Brain
With
Amyloid/biofilm
Plaques
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

22. Blood: Amyloid/biofilm
Brain Autopsy
Amyloid/biofilm
Blood: Amyloid/biofilm
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

23. Amyloid / Biofilm Units exist In Alzheimer’s Dementia
Summation:
Amyloid / Biofilm Units exist
In Alzheimer’s Dementia
Brain
Blood
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

24. Copyright © Alan B. MacDonald, M.D. October 9,2015 All rights Reserved
End of Lecture
Copyright © Alan B. MacDonald, M.D.
October 9,2015
All rights Reserved
Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved

25. Copyright (c) 2015 by Alan B. MacDonald, MD, FCAP, All Rights Reserved