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Fig. 1. —GO categories enriched in gene families showing high or low omega (dN/dS) values for Pneumocystis jirovecii. ... Fig. 1. —GO categories enriched.

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Presentation on theme: "Fig. 1. —GO categories enriched in gene families showing high or low omega (dN/dS) values for Pneumocystis jirovecii. ... Fig. 1. —GO categories enriched."— Presentation transcript:

1 Fig. 1. —GO categories enriched in gene families showing high or low omega (dN/dS) values for Pneumocystis jirovecii. ... Fig. 1. —GO categories enriched in gene families showing high or low omega (dN/dS) values for Pneumocystis jirovecii. The red line indicates the median (dN/dS) for all genes. GO categories are ordered from small to large NES (normalized enrichment scores) within each GO type (biological process, cellular component, and molecular function). Each box denotes the median and the 25% and 75% percentiles. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact Genome Biol Evol, Volume 10, Issue 6, 11 June 2018, Pages 1596–1606, The content of this slide may be subject to copyright: please see the slide notes for details.

2 Fig. 2. —Most genes in the biosynthesis of GPI show elevated omega rates. In red, we show those proteins having ... Fig. 2. —Most genes in the biosynthesis of GPI show elevated omega rates. In red, we show those proteins having higher omega rates. These proteins contribute to the statistical significance of the GO: term. In blue, we show those proteins not having higher rates of evolution. Hatched proteins were not included in GSEA. Gray proteins were not identified in Pneumocystis. Protein complexes are shown within dashed boxes. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact Genome Biol Evol, Volume 10, Issue 6, 11 June 2018, Pages 1596–1606, The content of this slide may be subject to copyright: please see the slide notes for details.

3 Fig. 3. —Episodic selection on Msg protein coding genes from Pneumocystis jirovecii. (A) Left tree shows variation in ... Fig. 3. —Episodic selection on Msg protein coding genes from Pneumocystis jirovecii. (A) Left tree shows variation in dN/dS. The length of the branches as well as the color is proportional to dN/dS. Right tree shows branch length proportional to genetic distance as estimated by Maximum-Likelihood (GTR + G+I model). Both trees have identical topologies. (B) Genetic distance versus dN/dS. While most branches evolve by negative selection (log10(dN/dS) < 0) a few branches evolve by strong positive selection (log10(dN/dS) > 1). Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact Genome Biol Evol, Volume 10, Issue 6, 11 June 2018, Pages 1596–1606, The content of this slide may be subject to copyright: please see the slide notes for details.

4 Fig. 4. —msg protein coding genes show a distinctive high G + C pattern in Pneumocystis jirovecii. Each gene from P. ... Fig. 4. —msg protein coding genes show a distinctive high G + C pattern in Pneumocystis jirovecii. Each gene from P. jirovecii was divided in 50 segments; and the G + C content of each segment was measured. In gray, we show the G + C content of 10 random samples of genes from P. jirovecii. Each random sample consists of 100 genes. The number of msg genes from families A1, A3(II), A3(III), B, D, and E is: 78, 9, 14, 11, 17, and 5, respectively. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact Genome Biol Evol, Volume 10, Issue 6, 11 June 2018, Pages 1596–1606, The content of this slide may be subject to copyright: please see the slide notes for details.

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