1. Additional Resources (Probiotics)
For Matt
5/21/2016

2. What is the optimal Probiotic?
NO single probiotic meets the needs in all patients
Consider the disease process
Decision should depend upon:
Metabolic insult of expected insult
Timing of delivery; pre, post, or both
Severity of condition
Expected duration of need
Tolerance
Function of GI tract remaining
Base decision on scientific evaluation of the data
-Dr. Martindale, 2010

3. Summary: Probiotics in Critical Illness
Probiotics must be evaluated;
Strain by Strain
Effect by Effect
Disease by Disease
Consider the term “Microbial Therapeutics”
When choosing a probiotic consider:
Preparation standards
Shipping conditions
Storage Environment
Claims justification
- Scientific Data, methods (FISH, 16s rRNA, etc)
-Dr. Martindale, 2010

4. General Guidelines for Use
Critically evaluate and use only when data supports
Do not extrapolate from one strain to another
Identify optimal strain, fiber, and commercially available product:
- Probiotic: viable cells per day
- Prebiotic: gm/day
Continued intake of probiotic may be required to maintain benefits
Prebiotic may be excellent option to modify flora on long term basis
-Dr. Martindale, 2010