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Aarti Saiganesh, BSc, Belinda J

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1 The Western environment reduces innate immune cytokine production in Chinese immigrants 
Aarti Saiganesh, BSc, Belinda J. Hales, PhD, Shu Chen, PhD, Emilija Filipovska-Naumovska, PhD, Gavin Pereira, PhD, Mathieu Garand, PhD, Tobias R. Kollmann, MD, Andrew J. Currie, PhD, Peter N. Le Souëf, MD, Guicheng Zhang, PhD  Journal of Allergy and Clinical Immunology  Volume 141, Issue 4, Pages e3 (April 2018) DOI: /j.jaci Copyright © Terms and Conditions

2 Fig 1 A, Number of mean cytokine measurements lower/higher in long-term compared with newly arrived immigrants. B, Individual and combined PC score differences in newly arrived and long-term immigrants in TLR ligands stratified as viral (R848, p:IC), gram-positive bacteria (PGN), and gram-negative bacteria (LPS). C, Individual and combined PC score differences in TH1 and TH17 cytokines in newly arrived and long-term immigrants. PC score differences between groups were measured using Mann-Whitney U tests. Bac, Bacteria; comb, combined; neg, negative; pos, positive. Journal of Allergy and Clinical Immunology  , e3DOI: ( /j.jaci ) Copyright © Terms and Conditions

3 Fig E1 Scatter plot showing PC1 and PC2 for the 21 cytokines that had a z-score difference of 0.2 or more between newly arrived and long-term immigrants. Journal of Allergy and Clinical Immunology  , e3DOI: ( /j.jaci ) Copyright © Terms and Conditions

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