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Making New Connections—Chromosome Conformation Capture for Identification of Disease-Associated Target Genes Matthew T. Patrick, Lam C. Tsoi, Johann E. Gudjonsson Journal of Investigative Dermatology Volume 139, Issue 3, Pages (March 2019) DOI: /j.jid Copyright © 2018 The Authors Terms and Conditions
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Figure 1 A summary of the various confirmation capture techniques and their methodologies. The method used by Jeng et al. (2018) uses Hi-C in combination of chromatin immunoprecipitation. The term one vs all refers to a definition of a single viewpoint, and the genome is screened for sequences that contact this selected site. The other terms are variation on this depending on the number of viewpoints being assessed and contact sites in the genome that are being assessed. 3C, chromosome conformation capture; 4C, chromosome confirmation capture-on-chip; 5C, chromosome confirmation capture carbon copy; ChIA-PET, chromatin interaction analysis with paired-end tag; ChIP, chromatin immunoprecipitation. Reproduced from Li et al. (2014), with permission. Copyright Cold Spring Harbor Laboratory Press. Journal of Investigative Dermatology , DOI: ( /j.jid ) Copyright © 2018 The Authors Terms and Conditions
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