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Defining the “sweet spot” for administered luteinizing hormone-to-follicle-stimulating hormone gonadotropin ratios during ovarian stimulation to protect.

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Presentation on theme: "Defining the “sweet spot” for administered luteinizing hormone-to-follicle-stimulating hormone gonadotropin ratios during ovarian stimulation to protect."— Presentation transcript:

1 Defining the “sweet spot” for administered luteinizing hormone-to-follicle-stimulating hormone gonadotropin ratios during ovarian stimulation to protect against a clinically significant late follicular increase in progesterone: an analysis of 10,280 first in vitro fertilization cycles  Marie D. Werner, M.D., Eric J. Forman, M.D., Kathleen H. Hong, M.D., Jason M. Franasiak, M.D., Thomas A. Molinaro, M.D., M.S.C.E., Richard T. Scott, M.D., H.C.L.D.  Fertility and Sterility  Volume 102, Issue 5, Pages (November 2014) DOI: /j.fertnstert Copyright © 2014 The Authors Terms and Conditions

2 Figure 1 The incidence of late follicular increase in P is significantly lower in cycles with an administered LH-to-FSH ratio between 0.30 and P<.001 for FSH only to 0.30–0.60; P<.001 for 0–0.30 to 0.30–0.60; P=.03 for 0.30–0.60 to >0.60. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2014 The Authors Terms and Conditions

3 Figure 2 The optimal ratio of exogenous LH-to-FSH to prevent a premature increase in P according to response group. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2014 The Authors Terms and Conditions


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