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Behavioral and Social Science Research NIMH Division of AIDS Research
Dianne Rausch, Ph.D. Director, Division of AIDS Research, National Institute of Mental Health @NIMHgov Share your thoughts on this presentation with #IAS2019
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No conflicts of interest
DISCLAIMER… No conflicts of interest
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NIMH Division of AIDS Research
The Division of AIDS Research (DAR) supports research to reduce the incidence of HIV/AIDS worldwide and to decrease the burden of living with HIV. Mental Health Neuroscience Behavioral Social Science Mental health is integral to prevention and treatment efforts across the lifespan Cognitive function Pathogenesis Cure Therapeutics Prevention cascade Treatment cascade Translation and implementation Biomedical intervention
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NIMH Division of AIDS Research
OAR Research Priorities Reduce the Incidence of HIV Research Toward HIV Cure Develop Next-Generation HIV Therapies Comorbidities, Coinfections, and Complications Cross-Cutting Areas National Institute of Drug Abuse (NIDA) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Child Health and Human Development (NICHD) …Many Other ICs National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Mental Health (NIMH) NIMH/DAR partners with trans-HHS colleagues to reduce the incidence of HIV/AIDS worldwide and to decrease the burden of living with HIV/AIDS.
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Mental Health and HIV Mental Illnesses Counseling Risk U=U Identity
Depression Comorbidities Identity Well-being Technology Outreach Counseling Cognition Disparities Mental Illnesses Individual Behavior Adherence U=U Attendance PrEP Empowerment Disclosure Risk Testing Retention Condoms Awareness Quality Key Populations Mental Health and HIV Emotional and Mental Health Interpersonal Factors and Structural Determinants Communication Beliefs Stigma Violence Culture Relationships Social Networks Incarceration Food Insecurity Economics Global Resources Mothers Adolescents Youth Adults Migrants Sex Workers Sexual and Gender Minorities Infants Ethnicity Race
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BSSR Functional Framework
Biological Individual Family Social Networks Community & Work National & State Global & Economic HIV/AIDS Prevention, Care, and Cure Supported by BSSR Domains Elemental Supportive Integrative BSSR BSSR BSSR Modifying vulnerable behaviors and environments Strengthening biomedical product acceptability Implementation of combination strategies Graphic adapted from: Gaist & Stirratt, 2017, JAIDS Basic BSSR: Understanding vulnerable populations and environments
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Violence and HIV HIV VIOLENCE Types of Past and Current Violence
Childhood Abuse Intimate Partner Violence Community Violence Among people at risk or living with HIV, trauma is associated with: Poor retention in prevention and treatment care continua Poor adherence to PrEP or ART reduced viral suppression Priority Populations Sexual and Gender Minorities Sex Workers Child-bearing Women Adolescents VIOLENCE HIV MAIN POINT: Having experienced trauma is associated with poorer retention in care, poorer medication adherence, and reduced viral suppression Additional info pulled from RFA: Research Gaps Co-occurring Conditions Modifiable Mechanisms Intervention Development
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HIV-related Health and Social Impacts: Stigma
Incidence, adherence, retention, morbidity, mortality, quality of life, social exclusion Affected Populations Organizations and Institutions Stigma Experiences Stigma Practices HIV-related stigma Intersecting Stigmas Race, gender, sexual orientation, occupation, class-related stigma Drivers & Facilitators Outcomes Manifestations Stigma ‘Marking’ Link to article: Individual Interpersonal Organizational Community Public Policy Adapted from: Stangl, A. L., Earnshaw, V. A., Logie, C. H., van Brakel, W., Simbayi, L. C., Barré, I., & Dovidio, J. F. (2019). BMC medicine, 17(1), 31.
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National Stakeholders Community Stakeholders
Community Engagement Global Stakeholders NGOs, WHO/UNAIDS, NIH, foundations National Stakeholders Ministries of Health, media, funders Broader Stakeholders NGOs, policymakers, professionals Community Stakeholders Family, friends, CBOs, CABs, Peers Trial Participant Adapted from: AVAC (2012) GPP Guidelines for Biomedical HIV Prevention Trials 2011
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Global Mental Health in HIV and Beyond
“There is no health without mental health” Task shifting and/or sharing and use of paraprofessionals Differentiated care/stepped care approaches Collaborative care to support the integrated care delivery Use of digital health/mobile technologies to support care delivery Use of transdiagnostic approaches to address multiple mental disorders in the same interventions Research Partnerships for Scaling Up Mental Health Interventions in Low- and Middle-Income Countries
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Current DAR Research Priorities
Emotional and Mental Health Individual Behavior Mental Health Comorbidities in HIV Prevention and Treatment Implementation Research for Screening and Treatment for Mental Disorders Development, Testing, Use, and Impact of Biomedical HIV Prevention, Treatment, and Cure Strategies Advancing Differentiated Care for Adolescents and Young Adults Interpersonal Factors and Structural Determinants Advanced Epidemiological Modeling Addressing the Impact of Violence on HIV Prevention and Treatment Understanding and Reducing Stigma to Improve the HIV Prevention and Care Continua
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Thank you
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