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A binding relationship with thrombin

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Presentation on theme: "A binding relationship with thrombin"— Presentation transcript:

1 A binding relationship with thrombin
by Jerry Ware Blood Volume 127(5): February 4, 2016 ©2016 by American Society of Hematology

2 Signaling-mediated cooperativity between platelet GPIb-IX and PAR1.
Signaling-mediated cooperativity between platelet GPIb-IX and PAR1. Depicted is a model for independent thrombin binding to 2 different platelet receptors that elicit mutually dependent signals via the Rac1-LIMK1 pathway. See Figure 6i in the article by Estevez et al that begins on page 626. Jerry Ware Blood 2016;127: ©2016 by American Society of Hematology


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