1. Distribution of mast cells around the terminal end bud of mice.
Distribution of mast cells around the terminal end bud of mice. Shown are formalin fixed, paraffin embedded sections stained with toluidine blue in which mast cells are identified by an enzymatic reaction to detect chymase a defining enzyme of these cells. (A) Mast cells (red arrows) shown in the fatty stroma in front of an invading terminal end bud (TEB]. (B) Many mast cells (red arrows) adjacent to developing mammary epithelium of mice at 5 wk of age. Black arrow shows a mast cell degranulating. (Panel A reprinted from Lilla and Werb [2010] and reprinted here with permission from Elsevier © 2010; panel B kindly provided by Dr. Zena Werb, USCF). Bar 50 µm.
Lisa M. Coussens, and Jeffrey W. Pollard Cold Spring Harb Perspect Biol 2011;3:a003285
©2011 by Cold Spring Harbor Laboratory Press