3. Connective tissue

4. Glycosaminoglycan

5. Collagen

6. Collagen Type Molecule Structural Features Representative Tissues
Composition
Fibrillar Collagens
I [α1(I)]2[α2(I)] 300-nm-long fibrils Skin, tendon, bone, ligaments,
dentin, interstitial tissues
II [α1(II)] nm-long fibrils Cartilage, vitreous humor
III [α1(III)] nm-long fibrils; Skin, muscle, blood vessels
often with type I
V [α1(V)] nm-long fibrils with Similar to type I; also cell
globular N-terminal cultures, fetal tissues
domain; often with type I
Fibril-Associated Collagens
VI [α1(VI)][α2(VI)] Lateral association with Most interstitial tissues
type I; periodic globular
domains
IX [α1(IX)][α2(IX)] Lateral association with Cartilage, vitreous humor
[α3(IX)] type II; N-terminal
globular domain; bound
glycosaminoglycan
Sheet-Forming Collagens
IV [α1(IV)]2[α2(IV)] Two-dimensional network All basal laminaes

8. Bone

9. Bone marrow

10. Hematopoiesis

15. Neuron

18. Synapse

20. Sarcoplasmic reticulum

21. Take home message
Neuronal structure
Neuromuscular junction