1. Perioperative cerebral oxygen saturation in neonates with hypoplastic left heart syndrome and childhood neurodevelopmental outcome 
George M. Hoffman, MD, Cheryl L. Brosig, PhD, Kathleen A. Mussatto, BSN, PhD, James S. Tweddell, MD, Nancy S. Ghanayem, MD 
The Journal of Thoracic and Cardiovascular Surgery 
Volume 146, Issue 5, Pages (November 2013)
DOI: /j.jtcvs
Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

2. Figure 1
Distribution of hourly cerebral saturation (rSO2C) in patients with normal and low performance on visual-motor integration (VMI) testing. Average values and distributions were lower in patients with low VMI scores (P < .05). See text for details.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

3. Figure 2
Temporal changes in early physiologic measures after stage 1 palliation (S1P) according to performance on visual-motor integration (VMI) testing in childhood. In patients with low performance on VMI testing, cerebral saturation (rSO2C) was consistently lower during 48 postoperative hours, arterial oxygen saturation (SaO2) lower, and heart rate (HR) higher during first 24 hours. No differences were seen in somatic/renal saturation (rSO2R), superior vena cava oxygen saturation (SvO2), mean arterial blood pressure (MABP), central venous/common atrial pressure (CVP), or arterial partial pressure of carbon dioxide (PaCO2). ns, Not significant; ANOVA, analysis of variance.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

4. Figure 3
Fractional polynomial models of physiologic parameters versus visual-motor integration (VMI) performance. Magnitude of effect of each parameter estimated as difference in nonoverlapped confidence intervals of model VMI. Significant effects are depicted as gray-shaded areas. CI, Confidence interval; rSO2C, cerebral oxygen saturation; SaO2, arterial oxygen saturation; ΔarSO2C, cerebral arterial-regional saturation difference; BP, mean arterial blood pressure; rSO2R, renal oxygen saturation; SavO2, arterial-venous saturation difference; ΔarSO2R, renal arterial-regional saturation difference.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

5. Figure 4
Multivariate model prediction of visual-motor integration (VMI) from hourly cerebral saturation (rSO2C). Predicted VMI was significantly lower with rSO2C less than 55%. Predicted VMI was normal (not different from 100) when hourly rSO2C was maintained at greater than 55%. Predicted VMI was normal with rSO2C greater than 45% and other standard risk conditions were applied. See text for details. CI, Confidence interval; SD, standard deviation.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions