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Periods of activation for the knee extensor (VL) and ankle extensor (GN) muscles with respect to foot-step contact (occurring at time zero) during stair ascent. Periods of activation for the knee extensor (VL) and ankle extensor (GN) muscles with respect to foot-step contact (occurring at time zero) during stair ascent. Values are mean and SD for healthy controls (C), diabetic patients with no neuropathy (D), and patients with DPN. *Significantly different (P < 0.05) timings compared with control group. Significance is shown for onset (asterisk before activation), TTP (asterisk above/below point of peak), and duration timings (asterisk after activation). For definition of the measured parameters, see Fig. 1. AE, ankle extensor; KE, knee extensor muscle. Joseph C. Handsaker et al. Dia Care 2014;37: ©2014 by American Diabetes Association
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