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Feverish Quest for Ebola Immunotherapy: Straight or Cocktail?

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Presentation on theme: "Feverish Quest for Ebola Immunotherapy: Straight or Cocktail?"— Presentation transcript:

1 Feverish Quest for Ebola Immunotherapy: Straight or Cocktail?
Erica Ollmann Saphire, M. Javad Aman  Trends in Microbiology  Volume 24, Issue 9, Pages (September 2016) DOI: /j.tim Copyright © 2016 Elsevier Ltd Terms and Conditions

2 Figure 1 Structure of the Trimeric Ebola Virus (here we are referring to the specific species, termed Ebola virus instead of the groups of ebolaviruses) (EBOV) Glycoprotein (GP). Different structural regions are color coded: glycan cap, blue; core GP1 containing the RBS, green; GP2, orange; tip of the internal fusion loop (IFL), pink; disordered cathepsin cleavage loop, red dotted line. Examples of reported EBOV GP monoclonal antibodies (mAbs) binding to different regions are listed. Trends in Microbiology  , DOI: ( /j.tim ) Copyright © 2016 Elsevier Ltd Terms and Conditions


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