Download presentation
Presentation is loading. Please wait.
1
Structures of four importers.
Structures of four importers. All transporters consist of four subunits, including a homodimer or heterodimer of IM subunits and a homodimer of NBD subunits. The ModB2C2 transporter is cocrystallized with ModA, a periplasmic BP in a closed, liganded conformation (cyan). The ligand, molybdate, is represented with a space-filling model. Maltose-BP (purple) is trapped in complex with MalFGK2 by using an E159Q substitution in MalK to prevent ATP hydrolysis (343). Nucleotide (ATP) is present only in MalFGK2E. A space-filling rendition of MalFGK2 is cut away to reveal an occluded pocket containing bound maltose. (Lower panel modified from reference 343.) Amy L. Davidson et al. Microbiol. Mol. Biol. Rev. 2008; doi: /MMBR
Similar presentations
© 2025 SlidePlayer.com. Inc.
All rights reserved.