1. General principles of surgical oncology
Kwok-Leung Cheung

2. No conflicts of interest in the past two years to disclose.
Disclosure
No conflicts of interest in the past two years to disclose.

5. Outline Surgery in context Principles of surgery
Challenges in geriatric oncology

6. Outline Surgery in context Principles of surgery
Challenges in geriatric oncology

7. Therapeutic options for solid malignancies*
Surgery
Radiotherapy
Systemic therapies – chemotherapy, endocrine therapy, targeted therapy, immunotherapy
*cf Haematological malignancies

8. Therapeutic options for solid malignancies*
Tumour – operability, biology and sensitivity to therapy
Patient – fitness, tolerability, choice
Logistics
Combinations and alternatives
*cf Haematological malignancies

9. Outline Surgery in context Principles of surgery
Challenges in geriatric oncology

10. Surgery in Oncology Mostly therapeutic cf diagnostic
‘Removal’ of tumour – curative versus palliative
Obtaining information (operative and pathological staging)
Reconstructive surgery cf organ transplant
Prophylactic surgery

11. Breast Surgery as a Model

12. Breast Surgery as a Model

13. Breast Surgery as a Model

14. Breast Surgery as a Model

15. Breast Surgery as a Model

16. Breast Surgery as a Model

17. Breast Surgery as a Model

18. Breast Surgery as a Model

19. Outline Surgery in context Principles of surgery
Challenges in geriatric oncology

20. Evidence Base Mainly retrospective cohorts
RCTs and GA-related studies emerging
Not much on health economics
Alternatives to radical surgery

21. better ones when to operate, and the best when not to operate.’
‘Good surgeons know how to operate,
better ones when to operate,
and the best when not to operate.’

22. Alternatives to Radical Surgery
No surgery or no treatment
Non-operative treatment
Minimally invasive surgery

23. Minimally Invasive Surgery

24. Minimally Invasive Surgery

25. Minimally Invasive Surgery

26. Selection

27. Factors contributing to postoperative complications
Age
Co-morbidities
Preoperative cognitive function
Intensity of surgery

28. Optimisation

29. Outline Surgery in context Principles of surgery
Challenges in geriatric oncology

30. Basics of Surgery in Geriatric Oncology
Part of a multi-modality approach
Achieving cure, palliation, staging, functional preservation and prevention
Ongoing challenges in obtaining a strong evidence base, selection and optimisation of patients as appropriate

31. by surgery: it will be something we will inject.’
‘’We shall never overcome cancer
by surgery:
it will be something
we will inject.’