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Anti-aging effects of ingenol mebutate for patients with actinic keratosis  Miri Kim, MD, PhD, Yujin Jung, MD, Jongsic Kim, MD, Seo-won Jeong, BS, Yu Ri.

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Presentation on theme: "Anti-aging effects of ingenol mebutate for patients with actinic keratosis  Miri Kim, MD, PhD, Yujin Jung, MD, Jongsic Kim, MD, Seo-won Jeong, BS, Yu Ri."— Presentation transcript:

1 Anti-aging effects of ingenol mebutate for patients with actinic keratosis 
Miri Kim, MD, PhD, Yujin Jung, MD, Jongsic Kim, MD, Seo-won Jeong, BS, Yu Ri Woo, MD, Hyun Jeong Park, MD, PhD  Journal of the American Academy of Dermatology  Volume 79, Issue 6, Pages (December 2018) DOI: /j.jaad Copyright © Terms and Conditions

2 Fig 1 Representative images before (left) and 8 weeks after (right) 3 treatments with ingenol mebutate gel. A, Clinical images of 69-year-old man who underwent treatment. B and C, Representative histologic images. (B, Hematoxylin-eosin stain; C, Masson trichrome stain; original magnification: ×100.) H&E, Hematoxylin-eosin; MT, Masson trichrome. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © Terms and Conditions

3 Fig 2 Real-time reverse transcription PCR to determine mRNA expression levels of type I collagen, TGF-β, and MMP-1. MMP-1, Matrix metalloproteinase 1; TGF-β, transforming growth factor-β. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © Terms and Conditions


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