1. The truncating mutation c
The truncating mutation c.661_662delGTinsTA that introduced a TAA stop codon into position 221 in the PALB2 gene identified by sequencing (left) and PTT (right).
The truncating mutation c.661_662delGTinsTA that introduced a TAA stop codon into position 221 in the PALB2 gene identified by sequencing (left) and PTT (right). Truncated polypeptide is indicated by a red arrowhead; wild-type (WT) translation product is indicated by a blue arrowhead; C–WT control.
Marketa Janatova et al. Cancer Epidemiol Biomarkers Prev 2013;22:
©2013 by American Association for Cancer Research