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Examining the Role of Pharmacokinetics in Hemophilia
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Role of PK Studies in Patients With Hemophilia
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The Science of Pharmacokinetics
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Pharmacokinetics
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Pharmacokinetic Definitions
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Hemophilia Overview
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Intermittent Infusions (Bolus)
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Continuous Infusions
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Half-Life Differences With Types of Factor VIII Deficiency Treatments
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Available Extended Half-Life Products for Factor VIII
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Half-Life Differences With Types of Factor IX Deficiency Treatments
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Available Extended Half-Life Products for Factor IX
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Assays for Hemophilia
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Factor Dosing General Overview
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Clinical Implications of PK Studies in Hemophilia Management
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Clinical Implications of PK Studies in Hemophilia Treatment
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PK Studies Optimize Treatment
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Personalized Prophylaxis
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Challenges of PK Studies
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Practical Approaches to PK Studies Peak/Trough Levels
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Practical Approaches to PK Studies Population PK Studies
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Planning Regimen With Patient/Family Factors to Consider
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Patient/Family Education
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Patient/Family Education and Participation
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Practical Implementation
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Role of Nurses and Pharmacists in PK Assessment
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Comprehensive Hemophilia Care Team
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Role of the HTC Team Pharmacist
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Role of the HTC Team Nursing
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Role of HTC Team (cont)
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Closing the Loop
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Abbreviations
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