1. LEfSe comparison analysis between the control and ciprofloxacin or vancomycin-imipenem groups at the end of antibiotic treatment (A or B, respectively) or 9 days after cessation of antibiotic treatment (C or D, respectively).
LEfSe comparison analysis between the control and ciprofloxacin or vancomycin-imipenem groups at the end of antibiotic treatment (A or B, respectively) or 9 days after cessation of antibiotic treatment (C or D, respectively). The red or green shading depicts bacterial taxa that were significantly higher in either the control, ciprofloxacin, or vancomycin-imipenem group, as indicated. The yellow circles on the cladogram depict bacterial taxa that were not significantly changed. Selection of discriminative taxa between the control and antibiotic groups were based on an LDA score cutoff of 3.0, and differences in the relative abundances of taxa were statistically determined based on a Mann-Whitney test at a significance level of 0.05.
Jocelyn M. Choo et al. mSphere 2017; doi: /mSphere