1. Risk Prediction of Complex Diseases from Family History and Known Susceptibility Loci, with Applications for Cancer Screening 
Hon-Cheong So, Johnny S.H. Kwan, Stacey S. Cherny, Pak C. Sham 
The American Journal of Human Genetics 
Volume 88, Issue 5, Pages (May 2011)
DOI: /j.ajhg
Copyright © 2011 The American Society of Human Genetics Terms and Conditions

2. Figure 1
Plots of Predicted Risks of Breast Cancer in the General Population and in Individuals with a Family History of Disease and with One Affected First-Degree Relative
Top: The probability density functions of predicted risks. Middle: The predictiveness curve (predicted risk plotted against the risk percentile). Bottom: the cumulative density functions of predicted risks. The horizontal line in the middle graph represents the average lifetime risk in the whole population. People with an affected first-degree relative are denoted by “Fam Hx +ve.”
The American Journal of Human Genetics  , DOI: ( /j.ajhg )
Copyright © 2011 The American Society of Human Genetics Terms and Conditions

3. Figure 2
Ten-Year Risk of Breast Cancer at Different Risk Percentiles for the General Female Population
The horizontal line represents the average 10-year risk of breast cancer for a 50-year-old woman.
The American Journal of Human Genetics  , DOI: ( /j.ajhg )
Copyright © 2011 The American Society of Human Genetics Terms and Conditions

4. Figure 3
Ten-Year Risk of Breast Cancer at Different Risk Percentiles for Women with One Affected First-Degree Relative
The horizontal line represents the average 10-year risk of breast cancer for a 50-year-old woman.
The American Journal of Human Genetics  , DOI: ( /j.ajhg )
Copyright © 2011 The American Society of Human Genetics Terms and Conditions