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A Novel Linkage to Generalized Vitiligo on 4q13-q21 Identified in a Genomewide Linkage Analysis of Chinese Families  Jian-Jun Chen, Wei Huang, Jin-Ping.

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Presentation on theme: "A Novel Linkage to Generalized Vitiligo on 4q13-q21 Identified in a Genomewide Linkage Analysis of Chinese Families  Jian-Jun Chen, Wei Huang, Jin-Ping."— Presentation transcript:

1 A Novel Linkage to Generalized Vitiligo on 4q13-q21 Identified in a Genomewide Linkage Analysis of Chinese Families  Jian-Jun Chen, Wei Huang, Jin-Ping Gui, Sen Yang, Fu-Sheng Zhou, Quan-Geng Xiong, Hong-Bo Wu, Yong Cui, Min Gao, Wei Li, Jin- Xian Li, Kai-Lin Yan, Wen-Tao Yuan, Shi-Jie Xu, Jian-Jun Liu, Xue-Jun Zhang  The American Journal of Human Genetics  Volume 76, Issue 6, Pages (June 2005) DOI: /430279 Copyright © 2005 The American Society of Human Genetics Terms and Conditions

2 Figure 1 Summary plot of the multipoint NPL and HLOD scores on 22 chromosomes from the genomewide linkage analysis of 382 microsatellite markers in 57 Chinese multiplex families with vitiligo. The American Journal of Human Genetics  , DOI: ( /430279) Copyright © 2005 The American Society of Human Genetics Terms and Conditions

3 Figure 2 Multipoint LOD scores on 4q13-q21 from the joint linkage analysis of 106 families. Multipoint NPL scores (red line); multipoint HLOD scores, under a recessive model of inheritance (black line); and marker information content (blue line) are plotted. The American Journal of Human Genetics  , DOI: ( /430279) Copyright © 2005 The American Society of Human Genetics Terms and Conditions


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