Download presentation
Presentation is loading. Please wait.
Published byMarja-Leena Lahti Modified over 5 years ago
1
Long-term outcomes in pediatric-onset esophageal eosinophilia
Charles W. DeBrosse, MD, James P. Franciosi, MD, MS, MSCE, Eileen C. King, PhD, Bridget K. Buckmeier Butz, MHSA, Allison B. Greenberg, BA, Margaret H. Collins, MD, J. Pablo Abonia, MD, Amal Assa’ad, MD, Philip E. Putnam, MD, Marc E. Rothenberg, MD, PhD Journal of Allergy and Clinical Immunology Volume 128, Issue 1, Pages (July 2011) DOI: /j.jaci Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions
2
Fig 1 Identification and recruitment of study participants. After histologic review of esophageal biopsy specimens obtained between 1982 and 1999, patients were categorized as having rEoE (≥15 eosinophils/hpf) or CE (<15 eosinophils/hpf). A healthy control group was also identified. Patients were then invited to complete validated outcome metrics. Journal of Allergy and Clinical Immunology , DOI: ( /j.jaci ) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions
3
Fig 2 Clinical features of the control, CE, rEoE, and DxEoE cohorts. Patients completed metrics for dysphagia (MDQ), food allergy, and quality of life (SF-12). The percentage of patients in the control, CE, and rEoE cohorts reporting dysphagia and food allergy, as well as median quality of life, were calculated (A). Data were reanalyzed with the subgroup of DxEoE removed from the rEoE and CE cohorts and classified independently (B). Journal of Allergy and Clinical Immunology , DOI: ( /j.jaci ) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions
4
Fig 3 Reported rates of dysphagia and peak esophageal eosinophil counts. Logistic regression analysis and receiver operating characteristic curves were generated to identify the relationship between dysphagia and peak esophageal eosinophil counts. The blue line represents the relationship between eosinophil counts and the probability of having dysphagia. Journal of Allergy and Clinical Immunology , DOI: ( /j.jaci ) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions
Similar presentations
© 2025 SlidePlayer.com. Inc.
All rights reserved.