1. RTA-specific serum IgG antibody titers and TNA in mice immunized with RiVax or RVEc. RTA-specific serum IgG titers after the second (A) or third (B) immunizations with indicated doses (10, 3, or 1 μg) of Alhydrogel-adsorbed RiVax or RVEc. (C) Prechallenge TNA EC50s in sera collected after three immunizations with RiVax or RVEc, as shown in panel B. (D) RTA-specific serum IgG GMTs after two immunizations with 0.3 μg of Alhydrogel-adsorbed RiVax or RVEc. An unpaired t test was used to compare the differences in serum IgG GMTs or TNA elicited by the same doses of RiVax and RVEc. *, P < 0.05, and ***, P <
RTA-specific serum IgG antibody titers and TNA in mice immunized with RiVax or RVEc. RTA-specific serum IgG titers after the second (A) or third (B) immunizations with indicated doses (10, 3, or 1 μg) of Alhydrogel-adsorbed RiVax or RVEc. (C) Prechallenge TNA EC50s in sera collected after three immunizations with RiVax or RVEc, as shown in panel B. (D) RTA-specific serum IgG GMTs after two immunizations with 0.3 μg of Alhydrogel-adsorbed RiVax or RVEc. An unpaired t test was used to compare the differences in serum IgG GMTs or TNA elicited by the same doses of RiVax and RVEc. *, P < 0.05, and ***, P <
Joanne M. O'Hara et al. Clin. Vaccine Immunol. 2013; doi: /CVI