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Volume 79, Issue 10, Pages (May 2011)

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Presentation on theme: "Volume 79, Issue 10, Pages (May 2011)"— Presentation transcript:

1 Volume 79, Issue 10, Pages 1113-1118 (May 2011)
Tubular markers do not predict the decline in glomerular filtration rate in type 1 diabetic patients with overt nephropathy  Stine E. Nielsen, Steen Andersen, Dietmar Zdunek, Georg Hess, Hans-Henrik Parving, Peter Rossing  Kidney International  Volume 79, Issue 10, Pages (May 2011) DOI: /ki Copyright © 2011 International Society of Nephrology Terms and Conditions

2 Figure 1 Design of the study.
Kidney International  , DOI: ( /ki ) Copyright © 2011 International Society of Nephrology Terms and Conditions

3 Figure 2 Scatter plot of baseline urinary neutrophil gelatinase-associated lipocalin (u-NGAL) versus decline in glomerular filtration rate (GFR) during the study period (R=0.32, P=0.02). Kidney International  , DOI: ( /ki ) Copyright © 2011 International Society of Nephrology Terms and Conditions

4 Figure 3 Scatter plot of baseline urinary kidney injury molecule-1 (u-KIM1) versus decline in glomerular filtration rate (GFR) during the study period (R=0.24, P=0.1). Kidney International  , DOI: ( /ki ) Copyright © 2011 International Society of Nephrology Terms and Conditions

5 Figure 4 Effect of losartan on tubular markers. (a) Reductions in log-transformed urinary kidney injury molecule-1 (u-KIM1) during losartan treatment. KIM1 is significantly decreased from baseline (no difference from 1 to 3 years). Error bars indicate 95% confidence interval. (b) Reductions in log-transformed u-KIM1 during losartan treatment, expressed in percentages. Kidney International  , DOI: ( /ki ) Copyright © 2011 International Society of Nephrology Terms and Conditions


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