1. Bacterial architecture and targets for biosensing.
Bacterial architecture and targets for biosensing. The cell wall of Gram-positive bacteria comprises a thick layer of peptidoglycan, which also contains lipids and other protein components, surrounding a lipid membrane. In contrast, Gram-negative bacteria possess a much thinner peptidoglycan layer sandwiched in between two cell membranes. The outer membrane contains proteins, such as porins, as well as lipopolysaccharides (LPS), also known as endotoxin. The inner membranes of both types of bacteria contain various proteins. Both types of bacteria may have flagella. Intracellular targets for biosensing include proteins, DNA, and RNA.
Asif Ahmed et al. Clin. Microbiol. Rev. 2014; doi: /CMR